“Some people are just genetically predisposed to alcoholism, I guess.”
You have a friend who drinks too much. You and another friend are talking about him. Your friend wonders why this guy has a drinking problem while other people don't, so you give your opinion.
Some people are just genetically predisposed to alcoholism, I guess.
You can end your sentence with "...I guess" when you're either not very sure about something:
A: It's not working.
B: You have to have a password, I guess.
You can also use this phrase when you're not happy about something:
I'll stay here and keep working, I guess.
Another phrase that you can use in this situation is "I suppose," which is a little more formal:
A: Is it OK if I send you the payment online?
B: Yeah, I suppose.
When a person can't stop drinking alcohol, we call that problem "alcoholism". You can use the word "alcoholism" like this:
Alcoholism and drug addiction are major issues in our society.
My family has a history of alcoholism.
A person who has this problem is "an alcoholic":
I'm a recovering alcoholic.
Being "genetically predisposed to" a health problem means that you're more likely to have that problem than most people because the problem runs in your family:
Some people are genetically predisposed to certain kinds of cancer.
This phrase sounds academic or scientific.
The word "genetically" comes from "gene", which is a piece of information that is passed from parents to children. Some other ways that we use "genetically" are:
- A genetically modified organism is a plant or animal whose genes have been changed by scientists.
- Identical twins are genetically identical because they have the same genes.
Being "predisposed to" something just means that that thing often happens. You can use it like this:
That breed of dog is naturally predisposed to violence.
I'm predisposed to believe people when they tell me something.